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RareCyte Orion
  • Up to 20 markers per pass: Fast. Economic. Tissue preserved.
  • Whole specimen imaging on standard glass slides
  • Same-section H&E imaging for morphology aligned to molecules
  • Flexible panel design for 100’s of panels that are easy to configure
The Orion platform delivers high-plex fluorescence imaging and biomarker analysis in a streamlined workflow for any research lab

Orion technology breaks barriers, providing rapid, straightforward, highly multiplexed whole slide tissue analysis, empowering researchers with unparalleled spatial resolution and flexibility for biomarker discovery.

Whether conducting multiplexed tissue imaging on slides or high-throughput analysis across cohorts, Orion enables rapid, high-quality spatial biology insights without the need for spectral unmixing. Leveraging its proprietary multi-epitope detection technology, Orion combines speed, simplicity, and scalability. 

Now available for high-throughput

 

Orion HT

The first high-plex spatial proteomics platform designed for clinical scale

Orion HT provides automated, high-capacity spatial proteomics with 24/7 hands-off operation, processing up to 30 slides. Its single-round, 20-channel imaging delivers high-plex biomarker data with high-throughput, panel flexibility, and data quality required for clinical and translational research.

Reliable Quantitative Data
  • - Preservation of tissue and antigen integrity
  • - Ultra-bright dyes and high-powered lasers, enabling sensitive detection of low-expression biomarkers.
  • - Standard protocols and direct conjugate staining, ensuring reproducible results.
FAST AND FLEXIBLE PANNEL DEVELOPMENT
  • - Single-round staining accelerates panel development
  • - Possibility of combination assembly of a broad portfolio of Orion antibody conjugates
  • - Incorporation of your custom biomarkers through simple conjugation chemistry
Biomarker Depth
  • - Functional, structural and phenotypic biomarkers within panels, analyzing tissue microenvironments
  • - Conservation of clinical samples through the measurement of variuos prognostic and predictive markers on a single tissue section

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From a wealth of applications we are presenting a small selection
of representative images leading to meaningful data.

If yours don't happen to be here, feel free to contact us.

Specifications

Orion

 

Sample compatibility: IF, IHC, H&E

Scan speed: 75 mins per cm2 at 20x

Excitation Lasers: 402 nm - 808 nm

Emission: Tunable from 425 - 894 nm

Slide compatibility: 1” x 3” x 1 mm, 25 mm x 75 mm x 1 mm

Slide capacity: 2 slides

Slide loading: Manual

Load repeatability: +/- 5.0 μm

Focus: Image-based Autofocus

Objectives: 4X 0.2 NA, 20X 0.8 NA

Camera: sCMOS; 2048 x 2048 pixels, 6.5 μm pixel size, 95% QE. 1.0 electron read noise

Safety: Class I LASER Product

File format: 16-bit OME .TIFF

 

Orion HT

- Same specifications as Orion, but 30 slides capacity

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